Clinical Labs & Metadata

Subject and Sample Metadata

Our clinical labs dataset results contain some sample-level metadata to enable connection between these results and samples used in other modalities. The sample.sampleKitGuid identifier is used across many data modalities:

Subject Metadata (prefix: subject)
subject.diseaseGroup: Which group each subject belonged to: Control (HC1); Control (HC2); ACPA+ At-risk (ARI); or ACPA+ Early RA (ERA)
subject.progressionGroup: For ARI subjects, whether subject was diagnosed with RA during the study period (converted): Progression (CONV) or No Progression (NONC)
subject.subjectID: A GUID for the Subject
subject.biologicalSex: The biological sex of the Subject
subject.diagnosisAge: For ARI-CONV subjects, age at diagnosis of RA
subject.diagnosisBMI: For ARI-CONV subjects, Body Mass Index at diagnosis of RA

Sample Metadata (prefix: sample)
sample.sampleKitGuid: A GUID for the Sample Kit, representing all material collected at a visit
sample.subjectAgeAtDraw: The age of the Subject in years at the time of sample collection

Clinical Lab Results

Data in the following columns of our table are results from clinical laboratory tests. Below, we show the column name, full name, units used, and normal ranges (where available). Normal ranges are provided as a guide, but may vary between clinical laboratories.

Anthropometric measures (prefix: am)

Colum Name	Full Name	Units
am.bmi	Body Mass Index (BMI)
am.height	Height	cm
am.weight	Weight	kg

 

Blood chemistry (prefix: chem)

Colum Name	Full Name	Units	Normal Range
chem.alt	Alanine Transaminase (ALT)	Units per L	7 - 52
chem.albumin	Albumin	g per dL	3.5 - 5.7
chem.alkaline_phosphatase	Alkaline Phosphatase	Units per L	39 - 117
chem.ast	Aspartate Aminotransferase (AST)	Units per L	12 - 39
chem.t_bili	Bilirubin, Total (T-Bili)	mg per dL	0.1 - 1.3
chem.bun	Blood Urea Nitrogen (BUN)	mg per dL	7 - 25
chem.calcium	Calcium	mg per dL	8.6 - 10.3
chem.co2	Carbon Dioxide (CO2)	mmol per L	21 - 31
chem.cl	Chloride (Cl)	mmol per L	98 - 108
chem.creatinine	Creatinine	mg per dL	0.7 - 1.3
chem.egfr_aa	Estimated Glomerular Filtration Rate (eGFR) - African American	ml per min per 1.73 m2	< 60
chem.egfr_non_aa	Estimated Glomerular Filtration Rate (eGFR) - Non-African American	ml per min per 1.73 m2	< 60
chem.globin	Globin	g per dL	2 - 3.5
chem.glucose	Glucose	mg per dL	70 - 199
chem.ldh	Lactate Dehydrogenase	Units	0 - 210
chem.magnesium	Magnesium	mg per dL	1.8 - 2.4
chem.phosphate	Phosphate	mg per dL	2.5 - 4.5
chem.potassium	Potassium	mmol per L	3.5 - 5.1
chem.protein	Protein, Total	g per dL	6.4 - 8.9
chem.sodium	Sodium	mmol per L	133 - 145

 

Blood Counts (prefix: bc)

Colum Name	Full Name	Units	Normal Range
bc.perc_basophils	% Basophils	percent
bc.perc_eosinophils	% Eosinophils	percent
bc.perc_lymphocytes	% Lymphocytes	percent
bc.perc_monocytes	% Monocytes	percent
bc.perc_neutrophils	% Neutrophils	percent
bc.basophil_count	Absolute Basophil Count	count per uL	0 - 202
bc.eosinophil_count	Absolute Eosinophil Count (AEC)	count per uL	0 - 400
bc.lymphocyte_count	Absolute Lymphocyte Count (ALC)	count per uL	1000 - 4800
bc.monocyte_count	Absolute Monocyte Count (AMC)	count per uL	200 - 900
bc.neutrophil_count	Absolute Neutrophil Count (ANC)	count per uL	1800 - 6600
bc.hematocrit	Hematocrit	percent	39.2 - 50.2
bc.hemoglobin	Hemoglobin	g per dL	12.1 - 18.1
bc.mch	Mean Corpuscular Hemoglobin (MCH)	pg	27.5 - 35.1
bc.mchc	Mean Corpuscular Hemoglobin Concentration (MCHC)	g per dL	32 - 36
bc.mcv	Mean Corpuscular Volume (MCV)	fL	80 - 100
bc.mpv	Mean Platelet Volume (MPV)	fL	7.2 - 11.7
bc.platelet_count	Platelet Count	thousand count per uL	150 - 400
bc.red_blood_cell_count	Red Blood Cell Count	million count per uL	4.18 - 6.09
bc.rdw	Red Cell Distribution Width (RDW)	percent	11.7 - 14.2
bc.wbc	White Blood Cell Count (WBC)	thousand count per uL	4 - 11.1

 

HCMV Serology (prefix: cmv)

Colum Name	Full Name
cmv.igg_serology	CMV IgG Serology Result (ELISA)
cmv.igg_serology_interpretation	CMV IgG Serology Result Interpretation

 

Inflammatory Markers (prefix: infl)

Colum Name	Full Name
infl.anti_ccp3	Anti-CCP3
infl.anti_ccp31	Anti-CCP31
infl.hs_crp	C-Reactive Protein, High-Sensitivity (HS-CRP)
infl.rf_iga_interpretation	RFIgA Interpretation
infl.rf_iga_result	RFIgA Result
infl.rf_igm_interpretation	RFIgM Interpretation
infl.rf_igm_result	RFIgM Result
infl.esr	SED Rate-Westergren (ESR)

 

Lipid Profile (prefix: lip)

Column Name	Full Name	Units	Normal Range
lip.cholesterol_hdl	Cholesterol, HDL	mg per dL	40 - 59
lip.cholesterol_ldl	Cholesterol, LDL	mg per dL	57 - 129
lip.cholesterol_non_hdl	Cholesterol, Non-HDL	mg per dL	0 - 189
lip.cholesterol_total	Cholesterol, Total	mg per dL	136 - 239
lip.chlesterol_hdl_ratio	Cholesterol/HDL Ratio	ratio
lip.triglycerides	Triglycerides	mg per dL	48 - 149