Along with blood samples, we collected plasma samples from each subject at each visit, which were interrogated using the Olink Explore 1536 plasma proteomics platform to measure relative abundance of plasma proteins.
Descriptors of the columns in our olink dataset can be found by clicking the header below:
Our plasma proteomics dataset contain some sample-level metadata to enable connection between these results and samples used in other modalities. The sample.sampleKitGuid identifier is used across many data modalities.
Sample Identifierssample.sampleKitGuid:
A Globally Unique Identifier (GUID) for the Sample Kit, representing all material collected at a visitspecimen.specimenGuid:
A GUID for the plasma specimen submitted for analysis
Olink Data (prefix: olink)olink.batch_id:
Batch submission IDolink.plate_id:
Plate submission IDolink.panel:
Olink Panel Nameolink.assay:
Olink Assay Name/Protein Nameolink.assay_id:
Olink Assay IDolink.uniprot_id:
Uniprot Gene IDolink.norm_offset:
Offset computed for batch normalizationolink.NPX_raw:
Original NPX value reported by Olinkolink.NPX_norm:
NPX value adjusted by batch normalizationolink.LOD_raw:
Limit of Detection value reported by Olinkolink.LOD_norm:
Limit of Detection value adjusted by batch normalization
Subject and Sample Metadata (prefix: subject and sample)subject.diseaseGroup:
Disease status group (e.g. Healthy Control (HC1); At-Risk Individual (ARI))subject.progressionGroup:
Disease progression group (Converted to RA (CONV) or Non-converter (NONC))subject.subjectID:
A GUID for the Subjectsubject.diagnosisAge:
Age of Subject in years at RA diagnosis (if applicable)subject.diagnosisBMI:
Body Mass Index of Subject in years at RA diagnosis (if applicable)subject.biologicalSex:
The biological sex of the Subjectsample.daysToDiagnosis:
Days between sample draw and clinical diagnosis of RA (if applicable)sample.daysSinceFirstVisit:
Days between initial sample draw and sample collectionsample.subjectAgeAtDraw:
Age of subject at the time of sample collection
Select Cinical Lab Results (prefix am and infl)am.bmi:
Anthropometric Measure: Subject Body Mass Index (BMI)infl.anti_ccp3:
Inflammatory Markers: Anti-CCP3infl.rf_iga_result:
Inflammatory Markers: RFIgA Resultinfl.rf_igm_result:
Inflammatory Markers: RFIgM Result
ALTRA and Sound Life Olink Data
File Name | Description | Download Link |
---|---|---|
aifi_altra_sound-life_olink.csv | Olink from all samples under study |