Along with blood samples, we collected plasma samples from each Sound Life subject at each visit, which were interrogated using the Olink Explore 1536 plasma proteomics platform to measure relative abundance of plasma proteins.
Descriptors of the columns in our olink dataset can be found by clicking the header below:
Our plasma proteomics dataset contain some sample-level metadata to enable connection between these results and samples used in other modalities. The sample.sampleKitGuid identifier is used across many data modalities.
Sample Identifierscohort.cohortGuid: A Globally Unique Identifier (GUID) for the cohort that the subject is a part of (BR1 = Young Adult; BR2 = Older Adult)sample.sampleKitGuid: A GUID for the Sample Kit, representing all material collected at a visitspecimen.specimenGuid: A GUID for the plasma specimen submitted for analysis
Olink Data (prefix: olink)olink.batch_id: Batch submission IDolink.plate_id: Plate submission IDolink.panel: Olink Panel Nameolink.assay: Olink Assay Name/Protein Nameolink.assay_id: Olink Assay IDolink.uniprot_id: Uniprot Gene IDolink.norm_offset: Offset computed for batch normalizationolink.NPX_raw: Original NPX value reported by Olinkolink.NPX_norm: NPX value adjusted by batch normalizationolink.LOD_raw: Limit of Detection value reported by Olinkolink.LOD_norm: Limit of Detection value adjusted by batch normalization
Subject and Sample Metadata (prefix: subject)subject.subjectGuid: A GUID for the Subjectsubject.biologicalSex: The biological sex of the Subjectsubject.birthYear: The Birth Year of the Subjectsubject.ageAtFirstDraw: The Age of the Subject at their first on-study sample collectionsubject.ageGroup: The Age Group of the Subject (Young Adult or Older Adult)subject.race: The self-reported Race of the Subjectsubject.ethnicity: The self-reported Ethnicity of the subjectsubject.cmv: The CMV Status of the subject, as determined by an HCMV assay
Sample Metadata (prefix: sample)sample.visitName: The name of the study visit (i.e. time point)sample.drawYear: The year of the study visit (e.g. 2021)sample.subjectAgeAtDraw: Age of subject at the time of sample collectionsample.daysSinceFirstVisit: Days between initial sample draw and sample collection
Sound Life Olink Data
| File Name | Description | Download Link |
|---|---|---|
| sound_life_all_olink.csv | Olink Explore 1536 data from the Sound Life cohort |
For each Immunobiology of Aging subject, plasma samples were collected and interrogated using the Olink Explore 3072 plasma proteomics platform to measure relative abundance of plasma proteins.
The Olink Explore 3072 panel contains all of the same assays as the Olink Explore 1536 panel used for the Sound Life cohort, as well as additional assays for targets that are not present in the Explore 1536 panel.
Descriptors of the columns in our olink dataset can be found by clicking the header below:
Our plasma proteomics dataset contain some sample-level metadata to enable connection between these results and samples used in other modalities. The sample.sampleKitGuid identifier is used across many data modalities.
Sample Identifierscohort.cohortGuid: A Globally Unique Identifier (GUID) for the cohort that the subject is a part of (SF4 = Immunobiology of Aging)sample.sampleKitGuid: A GUID for the Sample Kit, representing all material collected at a visitspecimen.specimenGuid: A GUID for the plasma specimen submitted for analysis
Olink Data (prefix: olink)olink.batch_id: Batch submission IDolink.plate_id: Plate submission IDolink.panel: Olink Panel Nameolink.assay: Olink Assay Name/Protein Nameolink.assay_id: Olink Assay IDolink.uniprot_id: Uniprot Gene IDolink.norm_offset: Offset computed for batch normalizationolink.NPX_raw: Original NPX value reported by Olinkolink.NPX_norm: NPX value adjusted by batch normalizationolink.LOD_raw: Limit of Detection value reported by Olinkolink.LOD_norm: Limit of Detection value adjusted by batch normalization
Subject and Sample Metadata (prefix: subject)subject.subjectGuid: A GUID for the Subjectsubject.biologicalSex: The biological sex of the Subjectsubject.ageAtFirstDraw: The Age of the Subject at their first on-study sample collectionsubject.race: The self-reported Race of the Subjectsubject.ethnicity: The self-reported Ethnicity of the subjectsubject.cmv: The CMV Status of the subject, as determined by an HCMV assay
Sample Metadata (prefix: sample)sample.visitName: The name of the study visit (i.e. time point)sample.subjectAgeAtDraw: Age of subject at the time of sample collectionsample.daysSinceFirstVisit: Days between initial sample draw and sample collection
Immunobiology of Aging Olink Data
| File Name | Description | Download Link |
|---|---|---|
| imm-of-aging_all_olink.csv | Olink Explore 3072 data from the Immunobiology of Aging cohort |